WEB-based GEne SeT AnaLysis Toolkit
 
Translating gene lists into biological insights...
 


User data and parameters: User data: textAreaUpload.txt, Organism: hsapiens, Id Type: ensembl_gene_stable_id, Ref Set: entrezgene, Significance Level: Top10, Statistics Test: Hypergeometric, MTC: BH, Minimum: 2

The results for each enriched gene sets are listed in this table.
For each gene set, the first row lists database name, gene set name , and corresponding gene set ID. The second row lists the following statistics:
Finally, genes in the gene set are listed. For each gene, the table lists the user uploaded ID and value (optional), Entrez ID, Ensembl Gene Stable ID, Gene symbol, and description. Ensembl Gene Stable ID and Entrez Gene ID are linked to the Ensembl and Entrez Gene databases, respectively.

Database:Transcription Target       Name:hsa_GGGCGGR_V$SP1_Q6       ID:DB_ID:2452
C=2891; O=19; E=5.16; R=3.68; rawP=5.53e-07; adjP=5.81e-05
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000172845 NA SP3 Sp3 transcription factor 6670 ENSG00000172845
2  ENSG00000127527 NA EPS15L1 epidermal growth factor receptor pathway substrate 15-like 1 58513 ENSG00000127527
3  ENSG00000179526 NA SHARPIN SHANK-associated RH domain interactor 81858 ENSG00000179526
4  ENSG00000120370 NA GORAB golgin, RAB6-interacting 92344 ENSG00000120370
5  ENSG00000180900 NA SCRIB scribbled homolog (Drosophila) 23513 ENSG00000180900
6  ENSG00000125755 NA SYMPK symplekin 8189 ENSG00000125755
7  ENSG00000160460 NA SPTBN4 spectrin, beta, non-erythrocytic 4 57731 ENSG00000160460
8  ENSG00000163719 NA MTMR14 myotubularin related protein 14 64419 ENSG00000163719
9  ENSG00000204231 NA RXRB retinoid X receptor, beta 6257 ENSG00000204231
10  ENSG00000169696 NA ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1 79058 ENSG00000169696
11  ENSG00000187147 NA RNF220 ring finger protein 220 55182 ENSG00000187147
12  ENSG00000171097 NA CCBL1 cysteine conjugate-beta lyase, cytoplasmic 883 ENSG00000171097
13  ENSG00000164144 NA ARFIP1 ADP-ribosylation factor interacting protein 1 27236 ENSG00000164144
14  ENSG00000008056 NA SYN1 synapsin I 6853 ENSG00000008056
15  ENSG00000130304 NA SLC27A1 solute carrier family 27 (fatty acid transporter), member 1 376497 ENSG00000130304
16  ENSG00000121481 NA RNF2 ring finger protein 2 6045 ENSG00000121481
17  ENSG00000148356 NA LRSAM1 leucine rich repeat and sterile alpha motif containing 1 90678 ENSG00000148356
18  ENSG00000106546 NA AHR aryl hydrocarbon receptor 196 ENSG00000106546
19  ENSG00000115355 NA CCDC88A coiled-coil domain containing 88A 55704 ENSG00000115355


Database:Transcription Target       Name:hsa_SCGGAAGY_V$ELK1_02       ID:DB_ID:2413
C=1176; O=11; E=2.10; R=5.24; rawP=7.63e-06; adjP=0.0004
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000029364 NA SLC39A9 solute carrier family 39 (zinc transporter), member 9 55334 ENSG00000029364
2  ENSG00000125826 NA RBCK1 RanBP-type and C3HC4-type zinc finger containing 1 10616 ENSG00000125826
3  ENSG00000171097 NA CCBL1 cysteine conjugate-beta lyase, cytoplasmic 883 ENSG00000171097
4  ENSG00000145916 NA RMND5B required for meiotic nuclear division 5 homolog B (S. cerevisiae) 64777 ENSG00000145916
5  ENSG00000164144 NA ARFIP1 ADP-ribosylation factor interacting protein 1 27236 ENSG00000164144
6  ENSG00000103932 NA RPAP1 RNA polymerase II associated protein 1 26015 ENSG00000103932
7  ENSG00000204439 NA C6orf47 chromosome 6 open reading frame 47 57827 ENSG00000204439
8  ENSG00000121481 NA RNF2 ring finger protein 2 6045 ENSG00000121481
9  ENSG00000132153 NA DHX30 DEAH (Asp-Glu-Ala-His) box polypeptide 30 22907 ENSG00000132153
10  ENSG00000163719 NA MTMR14 myotubularin related protein 14 64419 ENSG00000163719
11  ENSG00000204231 NA RXRB retinoid X receptor, beta 6257 ENSG00000204231


Database:Transcription Target       Name:hsa_GCCATNTTG_V$YY1_Q6       ID:DB_ID:2459
C=419; O=6; E=0.75; R=8.02; rawP=0.0001; adjP=0.0035
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000008838 NA MED24 mediator complex subunit 24 9862 ENSG00000008838
2  ENSG00000184209 NA SNRNP35 small nuclear ribonucleoprotein 35kDa (U11/U12) 11066 ENSG00000184209
3  ENSG00000011243 NA AKAP8L A kinase (PRKA) anchor protein 8-like 26993 ENSG00000011243
4  ENSG00000204231 NA RXRB retinoid X receptor, beta 6257 ENSG00000204231
5  ENSG00000100395 NA L3MBTL2 l(3)mbt-like 2 (Drosophila) 83746 ENSG00000100395
6  ENSG00000185122 NA HSF1 heat shock transcription factor 1 3297 ENSG00000185122


Database:Transcription Target       Name:hsa_RYTTCCTG_V$ETS2_B       ID:DB_ID:2415
C=1074; O=8; E=1.92; R=4.17; rawP=0.0007; adjP=0.0158
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000172845 NA SP3 Sp3 transcription factor 6670 ENSG00000172845
2  ENSG00000141380 NA SS18 synovial sarcoma translocation, chromosome 18 6760 ENSG00000141380
3  ENSG00000198276 NA UCKL1 uridine-cytidine kinase 1-like 1 54963 ENSG00000198276
4  ENSG00000131584 NA ACAP3 ArfGAP with coiled-coil, ankyrin repeat and PH domains 3 116983 ENSG00000131584
5  ENSG00000100395 NA L3MBTL2 l(3)mbt-like 2 (Drosophila) 83746 ENSG00000100395
6  ENSG00000204439 NA C6orf47 chromosome 6 open reading frame 47 57827 ENSG00000204439
7  ENSG00000116871 NA MAP7D1 MAP7 domain containing 1 55700 ENSG00000116871
8  ENSG00000115355 NA CCDC88A coiled-coil domain containing 88A 55704 ENSG00000115355


Database:Transcription Target       Name:hsa_GGAMTNNNNNTCCY_UNKNOWN       ID:DB_ID:2269
C=117; O=3; E=0.21; R=14.36; rawP=0.0012; adjP=0.0158
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000187147 NA RNF220 ring finger protein 220 55182 ENSG00000187147
2  ENSG00000132153 NA DHX30 DEAH (Asp-Glu-Ala-His) box polypeptide 30 22907 ENSG00000132153
3  ENSG00000125755 NA SYMPK symplekin 8189 ENSG00000125755


Database:Transcription Target       Name:hsa_V$NFKB_Q6_01       ID:DB_ID:2259
C=231; O=4; E=0.41; R=9.70; rawP=0.0008; adjP=0.0158
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000187147 NA RNF220 ring finger protein 220 55182 ENSG00000187147
2  ENSG00000088808 NA PPP1R13B protein phosphatase 1, regulatory subunit 13B 23368 ENSG00000088808
3  ENSG00000163719 NA MTMR14 myotubularin related protein 14 64419 ENSG00000163719
4  ENSG00000131584 NA ACAP3 ArfGAP with coiled-coil, ankyrin repeat and PH domains 3 116983 ENSG00000131584


Database:Transcription Target       Name:hsa_V$PAX_Q6       ID:DB_ID:2284
C=252; O=4; E=0.45; R=8.89; rawP=0.0011; adjP=0.0158
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000187147 NA RNF220 ring finger protein 220 55182 ENSG00000187147
2  ENSG00000127663 NA KDM4B lysine (K)-specific demethylase 4B 23030 ENSG00000127663
3  ENSG00000160460 NA SPTBN4 spectrin, beta, non-erythrocytic 4 57731 ENSG00000160460
4  ENSG00000122641 NA INHBA inhibin, beta A 3624 ENSG00000122641


Database:Transcription Target       Name:hsa_V$GATA2_01       ID:DB_ID:1891
C=104; O=3; E=0.19; R=16.16; rawP=0.0009; adjP=0.0158
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000172845 NA SP3 Sp3 transcription factor 6670 ENSG00000172845
2  ENSG00000125755 NA SYMPK symplekin 8189 ENSG00000125755
3  ENSG00000008056 NA SYN1 synapsin I 6853 ENSG00000008056


Database:Transcription Target       Name:hsa_TATAAA_V$TATA_01       ID:DB_ID:2456
C=1276; O=7; E=2.28; R=3.07; rawP=0.0078; adjP=0.0564
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000120370 NA GORAB golgin, RAB6-interacting 92344 ENSG00000120370
2  ENSG00000011243 NA AKAP8L A kinase (PRKA) anchor protein 8-like 26993 ENSG00000011243
3  ENSG00000164144 NA ARFIP1 ADP-ribosylation factor interacting protein 1 27236 ENSG00000164144
4  ENSG00000125755 NA SYMPK symplekin 8189 ENSG00000125755
5  ENSG00000198276 NA UCKL1 uridine-cytidine kinase 1-like 1 54963 ENSG00000198276
6  ENSG00000115355 NA CCDC88A coiled-coil domain containing 88A 55704 ENSG00000115355
7  ENSG00000122641 NA INHBA inhibin, beta A 3624 ENSG00000122641


Database:Transcription Target       Name:hsa_TGTTTGY_V$HNF3_Q6       ID:DB_ID:2423
C=733; O=5; E=1.31; R=3.82; rawP=0.0101; adjP=0.0564
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000177169 NA ULK1 unc-51-like kinase 1 (C. elegans) 8408 ENSG00000177169
2  ENSG00000171097 NA CCBL1 cysteine conjugate-beta lyase, cytoplasmic 883 ENSG00000171097
3  ENSG00000132153 NA DHX30 DEAH (Asp-Glu-Ala-His) box polypeptide 30 22907 ENSG00000132153
4  ENSG00000122641 NA INHBA inhibin, beta A 3624 ENSG00000122641
5  ENSG00000204231 NA RXRB retinoid X receptor, beta 6257 ENSG00000204231




WebGestalt is currently developed and maintained by Jing Wang and Bing Zhang at the Zhang Lab. Other people who have made significant contribution to the project include Dexter Duncan, Stefan Kirov, Zhiao Shi, and Jay Snoddy.

Funding credits: NIH/NIAAA (U01 AA016662, U01 AA013512); NIH/NIDA (P01 DA015027); NIH/NIMH (P50 MH078028, P50 MH096972); NIH/NCI (U24 CA159988); NIH/NIGMS (R01 GM088822).